Prime 50+ · formulated by a pharmacist
50 and 60. 30 Comrades between them. One skincare routine.
The whole Prime routine in one box. About two minutes, morning and evening. Every formula is written by Dr Joan van Wyngaard, a pharmacist, in George, with each key active at the level it was tested at.

Your two minutes
The same serums morning and evening. Only the cream changes.
Morning
Start here
The full routine, or the two serums that do the most work after 50.
The Complete Prime RitualCream Cleanser, Wrinkle Relaxant, DNA Defence, SkinSmart SPF 30 and Restorative Moisturiser in one box.R1,810
Wrinkle Relaxant 20 mlMore radiant skin in 41 of 41 women: +20% by day 56 (placebo +4%)*R540
DNA Defence Serum 30 mlCrow’s-feet depth −10.5% in 7 days (placebo −3.7%)*R450DNA Defence · ALGAKTIV® Vitalys™ 2%
How DNA Defence works on the signs of ageing
Ageing starts inside the cell. Vitalys™ supports the skin’s own renewal at each step. Lab tests show how. Studies on women aged 50 to 65 show what you see.
Lines and wrinkles
Helps skin cells clear DNA damage faster. LAB
−10.5% in 7 days
crow’s-feet depth (placebo −3.7%); −13.7% at 28 days (placebo −6.1%) CLINICAL
Loss of firmness
Helps skin cells make more collagen: type I +22%, type III +12%. LAB
21 of 21 women
had firmer skin at 28 days (−9.6% vs placebo −5.3%). At 2%, the level in DNA Defence: firmness +17.7% CLINICAL
Tired, dull skin
Raises NAD⁺, the cell’s renewal fuel, by about a third, and helps stressed cells keep their own antioxidant defence. LAB
+29.9% radiance
(placebo +18.4%) CLINICAL
Dark spots and uneven tone
Helps pigment cells make less melanin: −33%. LAB
+17.5% lighter spots
(placebo +8.3%); more even tone +11.6% (placebo +5.3%) CLINICAL
Rough texture
−9.9% roughness
at 28 days (placebo −3.3%) CLINICAL
Jawline and neck
Neck firmer −7.6%
at day 14 (placebo −1.6%), in a small group; less jawline sagging in both studies CLINICAL
Eye-area skin looked about 4 years younger after 28 days (placebo 1.8 years).
DNA Defence – R450More for 50+ skin
Add one step when you want more.
Restorative Moisturiser 50 mlDid as well as 0.3% retinol in 56 days: crow’s feet −18.7% (retinol −16.2%)*R410
Collagen QuenchLeave-on jelly mask. Crow’s-feet depth −13.7% in 10 minutes (placebo −4.7%)*R430
Lifting Eye CreamWith ALGAKTIV® UpLift™ at 1%, caffeine, panthenol and rose water. After the serums.R340
Bedtime Booster 20 mlOur only true vitamin-A retinoid, with niacinamide and bakuchiol. Nights only.R450
Lip Defence NEWFuller lips in 15 minutes: +16.3% (placebo +7.1%)*R160
Prime Lip & Eye DuoLip Defence and the Lifting Eye Cream together.R440Prime serum combos
The serums that do the most work after 50, together.
The Three Serums at 50Wrinkle Relaxant, DNA Defence and the Hair Regrowth Serum. Lines, firmness and hair.R1,130
Prime Serum DuoWrinkle Relaxant for the lines you mind, DNA Defence for face and neck.R850
Face & Hair DuoDNA Defence with the Hair Regrowth Serum. For thinning hair too.R670
Wrinkles & Hydration ComboTwo 20 ml Wrinkle Relaxants.R800
Nighttime Replenish & RenewBedtime Booster and Wrinkle Relaxant, for nights when you want more.R880Breaking out again?
Breakouts can come back around menopause. Keep your routine and treat the spots, not the whole face.
FAQ
Is this range only for women in menopause?
No. It is built for skin that has become drier, thinner and slower to repair, and that usually starts around menopause. Most of the studies behind these actives were run on women over 35, and the DNA Defence study on women aged 50 to 65.
Do I need to add a retinol?
No. RetinART™, our bio-retinoid, is already in both the SkinSmart Day Cream and the Restorative Moisturiser, so your skin gets retinoid care morning and night without a separate product.
Want an extra boost? Add the Bedtime Booster at night, after your serums and before the Restorative Moisturiser. It contains hydroxypinacolone retinoate, a retinoid that needs no conversion in your skin, with niacinamide and bakuchiol. Start with two nights a week and build up slowly to every night. You can also take it with the Wrinkle Relaxant in the Nighttime Replenish & Renew combo.
When will I see a difference?
Skin feels softer within the first week. The DNA Defence active showed a measurable change in crow’s-feet depth at seven days, and most people see it clearly at four weeks. Use it twice a day, every day, and the results will follow. The studies just verified it.
I’m breaking out again. Is that part of it?
It often is: breakouts can come back around menopause. Keep your routine, and add the Smoothing Gel at night and Clear Wish on the blemishes. Treat the spots, not the whole face.
My hair is thinning too. Is there something for that?
Yes. The Hair Regrowth Serum is made for thinning hair, and it shares the blue bottle with DNA Defence because it was made for the same customer. Take the two together in the Face & Hair Duo, or all three serums in The Three Serums at 50.
GROWN, NOT HARVESTED
It starts with microalgae
Five of the actives in this range are grown from microalgae in sealed glass tanks: the same batch in June and in December.
Vitant was the first in South Africa to use ALGAKTIV® actives.
Three bosses, fired without warning
What menopause does to your skin, and the rest of you. By Dr Joan van Wyngaard
LAB = tests in skin cells or a test tube (ALGAKTIV® Vitalys™ brochure). CLINICAL = studies on people against placebo.
* DNA Defence: ALGAKTIV® Vitalys™ at 1%, Complife Italia IT0006889/24B, 21 women aged 50–65, split face against placebo, twice daily, 28 days; skin age read from crow’s-feet wrinkle depth. Radiance, dark spots, even tone and jawline: Complife Asian study, 22 women aged 50–65, at 1%. Neck: small group. Firmness at 2%, the level in DNA Defence: ALGAKTIV® study, 10 women, once daily in the evening, 28 days, against placebo.
* Wrinkle Relaxant: ALGAKTIV® Exometics™ G 2%, Complife Italia IT0005884/24, 41 women aged 35–57, split face against placebo, twice daily, 56 days.
* Restorative Moisturiser: ALGAKTIV® RetinART™ 2% (CL2022 1%) vs 0.3% retinol, Complife Italia IT0005019/21, 30 women over 40, split face, twice daily, 56 days; no significant difference between the two.
* Collagen Quench: ALGAKTIV® Collage™ at 3%, the level in the mask, one application, against placebo.
* Lip Defence: ALGAKTIV® Rubinity® 1%, Complife Italia IT0004391/25, 22 women on Rubinity® and 22 on placebo, aged 45–70, twice daily, 28 days.



